The PREMUROSA project aims to train a new generation of scientists with an integrated vision of the whole value chain in musculo-skeletal regeneration technologies and able to boost the necessary innovations to achieve precision principles in developing innovative devices and optimized clinical applications. Treatment of musculo-skeletal disorders is currently based either on prosthetic or regenerative surgical procedures, often involving medical device implantation. A great improvement could be achieved by precision medicine, specifically designed on patient’s individual characteristics. The new scientists trained in PREMUROSA will be able to push the innovations required for personalized and precision principles in the development of innovative devices, their testing and optimized clinical applications that currently completely lack. The project started in 2020 and this session will provide a possibility to present results achieved including biomaterials and medical devices developed within PREMUROSA.